Cole is a main character in the InFamous video game series published by Sony Computer Entertainment; he appears as the main protagonist of 2009's InFamous and 2011's InFamous 2. The series was created by Sucker Punch Games, a fellow first-party developer of Naughty Dog, who was said to have helped in the development of InFamous.
A key feature in the InFamous series is its Karma System, which, depends on Cole's choices, can turn him into either a hero, or a villain. Due to this, two versions of Cole appear in Uncharted 2's multiplayer; "Good Cole" and "Bad Cole."
Their appearances are based on Cole's Karma-related physical changes from 2009's InFamous, with Good Cole's clothes are lighter in color and he produces blue electricity from his arms, while Bad Cole's clothes are darker in color and he produces red electricity from his arms.
- In Good Cole's multiplayer card, he wields a Wes-44. In Bad Cole's multiplayer card, he is seen wielding an AK-47.
- In the InFamous series, due the electric current that constantly runs through his body, Cole is unable to use firearms due to his powers igniting and exploding gunpowder. In Uncharted 2's multiplayer, this is obviously not the case.