The Nazi U-boat seen in the Amazon.
A Nazi was a follower of the ideology of Nazism or National Socialism. Nazism was a unique variety of fascism that involved both biological racism and antisemitism. They originated in Germany.
The Nazis are an unseen presence in Uncharted: Drake's Fortune, as Nate finds one of their U-Boats in the Amazon. He quickly learns that they were looking for the treasure of El Dorado, and had mounted a second expedition to an island located at Kriegsmarine co-ordinate UK2642, which they referred to as Versteckte Insel (German for secret island). Upon arriving, they set to work and built a submarine bunker on the island. They quickly found the El Dorado statue and moved it from the treasure vault. However, they soon fell victim to its curse and were either killed by the descendants or mutated by the statue.
Karl Schäfer led a group of Nazis on an Ahnenerbe expedition to find the Cintamani Stone 70 years before the events of Among Thieves. After learning the truth about the Cintamani Stone, and after several of his men ate the resin from the tree of life; Schäfer shot and killed his entire expedition. He was severely wounded in the process and managed to make it to Tenzin's village, where he remained until Nathan Drake arrived 70 years later.
- The presence of Nazi Germany's involvement in searching for El Dorado and the Cintamani Stone is most likely an homage to the film Raiders of the Lost Ark, which was based on how the Nazis and Hilter's interest and beliefs that paranormal and religious (mostly Christian, Native American and Asian) objects would help them capture and control the world and possibly the Universe.