After Nathan, Chloe, Cutter (now injured with a broken leg) and Victor escaped the Citadel in Syria while being chased by Katherine Marlowe's agents, the four of them used a parked tour bus as a getaway vehicle. Sully took the driver's seat and Chloe questioned Nate on what he's trying to prove. It's here where Cutter told Nate that he will never forgive him if he gave up on his journey.
What happened to the bus after being stolen is unknown. Although, Sully did say he was planning on "dumping" it at a hidden place.
- A bus previously appeared in Uncharted 2: Among Thieves. It was used by the Resistance Fighters to try and run over some of Lazarevic's Soldiers in the beginning of Chapter 5 - Urban Warfare. It is also seen at the same place in Co-Op Objective in its turned over state.
- Inside the bus is a key chain of Sackboy (an easter egg reference from the LittleBigPlanet series).
Uncharted 3: Drake's Deception
- Chapter 9 - The Middle Way (ending cutscene)